Transdermal Drug Delivery System

Transdermal Drug Delivery System Market by Type (Transdermal Patches, Transdermal Semisolids), Application (Cardiovascular Diseases, Central Nervous System Disorders, Hormonal Applications), End User - Global Forecast 2024-2030

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[180 Pages Report] The Transdermal Drug Delivery System Market size was estimated at USD 6.98 billion in 2023 and expected to reach USD 7.32 billion in 2024, at a CAGR 5.06% to reach USD 9.87 billion by 2030.

Transdermal Drug Delivery System Market
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Transdermal drug delivery comprises the production, distribution, and application of therapeutic methods that facilitate the controlled release of medications through the skin. This innovative approach offers numerous advantages over conventional oral or intravenous drug administration, such as increased patient compliance, reduced side effects, and improved pharmacokinetic profiles. The TDDS encompasses various technologies, including passive diffusion systems, iontophoresis, microneedles, and ultrasound-mediated techniques. The increase in the aging population and the growing prevalence of chronic diseases necessitate more practical and convenient drug delivery methods. Furthermore, advancements in nanotechnology and materials science have enabled the development of sophisticated transdermal patches that offer superior drug permeation across biological membranes without causing irritation or discomfort to patients. However, high development costs associated with producing complex transdermal systems and incidences of product recalls may adversely impact their use in the healthcare sector. Besides, advanced drug delivery vehicles demonstrate promising potential to improve the bioavailability and solubility of water-soluble drugs, enabling more effective transdermal drug delivery strategies.

Transdermal Drug Delivery System Market - Global Forecast 2024-2030
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Type: Ongoing regulatory and government approvals for transdermal patches

Transdermal patches are adhesive-coated, medicated patches designed to deliver a specific drug dosage through the skin and into the bloodstream over an extended period. They offer several advantages over conventional oral and parenteral drug delivery systems, such as improved patient compliance, reduced side effects, and controlled release of active ingredients. Drug-in-adhesive patches, matrix patches, microneedle patches, and reservoir membrane patches are available and are used according to medical requirements. The preference for transdermal patches is mainly due to their non-invasive nature and ease of application. They are suitable for patients experiencing difficulties swallowing pills or for those with gastrointestinal issues that may affect the absorption of medications. Transdermal semisolids include gels, creams, and ointments formulated with drugs that are absorbed through the skin into the systemic circulation. These dosage forms offer benefits such as easy application and removal, localized treatment without systemic side effects for certain conditions, and flexibility in formulation. Transdermal patches provide more consistent drug release than semisolids since they possess a controlled-release mechanism. Additionally, patches show better adhesion to the skin surface than semisolids, which may require frequent reapplication of the gels or creams.

Application: Need for minimally invasive drug delivery systems for management of cardiovascular diseases

Transdermal drug delivery systems are preferred in treating cardiovascular diseases such as angina pectoris or hypertension due to their ability to maintain constant plasma medication levels with fewer side effects. Nitroglycerin patches have been extensively used for angina patients, offering continuous relief without the need for frequent oral administration. TDDS displays an enhanced potential in managing central nervous system disorders, including Parkinson's disease and Alzheimer's disease, by maintaining steady concentrations of drugs. The continuous delivery minimizes fluctuations observed with oral medications, which can lead to breakthrough symptoms or side effects. Hormonal applications of TDDS include contraception, hormone replacement therapy (HRT), and testosterone supplementation. Transdermal patches offer advantages in maintaining steady hormone levels, reducing side effects, and improving patient compliance. Transdermal systems have gained popularity in managing chronic pain conditions, including musculoskeletal disorders or cancer-related pain, due to their ability to deliver analgesics directly to the affected area for long durations while minimizing systemic side effects. Transdermal estrogen therapy is essential for hormone replacement therapy for menopausal symptoms or osteoporosis management in postmenopausal women.

End-User: Preference for self-administration of drugs leading to demand for drug delivery systems that can be implemented in home care settings

Transdermal drug delivery systems are being utilized within particular innovative clinics for skin care and are implemented into the more effective health care system. With the growing understanding of drug delivery and the continued efforts of medical doctors, engineers, and scientists to advance this technology, an ultrasound-based transdermal delivery platform is expected to be a step closer to clinical applications. Clinical impact relies on a transdermal delivery system that administers drugs safely and effectively, is low-cost and easy to use, and is designed for self-administration at home. Transdermal drug delivery has recently gained popularity due to its unique and advantageous properties, which provide prospective benefits over conventional routes of drug administration in the therapy of numerous illnesses in hospital settings. Hospitals and clinics serve several patients in rural regions, particularly senior populations. These pharmacists help patients at a higher risk of medication interactions or illness complications due to a lack of control over their condition.

Regional Insights

The transdermal drug delivery market is evolving in the Americas due to its well-established healthcare infrastructure and research & development activities. Regulatory bodies in the Americas ensure adherence to standard guidelines while approving new products, resulting in the development of innovative transdermal technologies. The APAC region has a growing demand for advanced healthcare technologies due to increasing disposable incomes, population aging, and the need for efficient treatments. The transdermal drug delivery system market is growing in the EMEA region due to the presence of pharmaceutical industries, increased healthcare spending, and the rapid expansion of its manufacturing capabilities for transdermal systems. Moreover, the increasing adoption of personalized medicine and targeted therapies presents further prospects for TDDS systems tailored to specific patient populations or disease conditions.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Transdermal Drug Delivery System Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Transdermal Drug Delivery System Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Recent Developments
  • Luye Pharma's Rivastigmine Twice Weekly Transdermal Patch Approved in China for the Treatment of Alzheimer's Disease

    Luye Pharma Group announced the approval of its Rivastigmine Twice Weekly Transdermal Patch by China's National Medical Products Administration (NMPA) for the treatment of mild to moderate Alzheimer's disease. This breakthrough originates from Luye's own European-based transdermal patch platform and is now set to serve the Chinese market, bolstered by the collaborative effort with Changchun GeneScience Pharmaceutical Co., Ltd. (GenSci). [Published On: 2023-10-31]

  • Satio Wins USD 3.5 Million Contract To Develop At-Home Transdermal Drug Delivery Device

    Satio's latest advancement in drug delivery technology, bolstered by a USD 3.5 million SBIR contract from the NIH's ARPA-H. The contract is aimed to fuel the development of SatioRx, a novel, compact, and cost-effective transdermal drug delivery device. This innovation stands apart with its disposable microneedle components that promise precise and painless medication dosing directly into the bloodstream, revolutionizing the way liquid drugs are administered transdermally. [Published On: 2023-09-28]

  • LTS Completes Its Entry Into Large Molecule Drug Delivery With The Acquisition Of The Sorrel Wearable Injection Device Business

    LTS has expanded its large molecule drug delivery portfolio by acquiring the Sorrel Wearable Injection Device Business. This acquisition includes exclusive intellectual property, engineering expertise, and commercialization capabilities related to the Sorrel device. With LTS's Transdermal Drug Delivery System, patients suffering from chronic diseases now have access to a non-invasive method of self-administering medications on a continuous basis. [Published On: 2023-06-08]

Key Company Profiles

The report delves into recent significant developments in the Transdermal Drug Delivery System Market, highlighting leading vendors and their innovative profiles. These include 3M Company, AdhexPharma, SAS, Bayer AG, Biotts Inc., Boehringer Ingelheim International GmbH, DuPont de Nemours, Inc., Gensco Pharma, Hisamitsu Pharmaceutical Co., Inc., IBSA Farmaceutici Italia Srl, IntelGenx Corp., Johnson & Johnson Services, Inc., Kindeva Drug Delivery L.P., Lavipharm S.A., Lead Chemical Co., Ltd., Luye Life Sciences Group, Medherant Limited, Nitto Denko Corporation, Novartis International AG, Nutriband Inc., Purdue Pharma L.P., Sorrento Therapeutics, Inc., Sparsha Pharma International Pvt. Ltd., Starton Therapeutics, Toa Eiyo Ltd., Toyo Ink SC Holdings Co., Ltd., Transdermal Therapeutics, Inc., UCB S.A., Viatris Inc., Zhongshan Senwell Bio Technology Co., Ltd., and Zynerba Pharmaceuticals, Inc..

Market Segmentation & Coverage

This research report categorizes the Transdermal Drug Delivery System Market to forecast the revenues and analyze trends in each of the following sub-markets:

  • Type
    • Transdermal Patches
      • Drug-In-Adhesive Patches
      • Matrix Patches
      • Microneedle Patches
      • Reservoir Membrane Patches
    • Transdermal Semisolids
      • Gels
      • Ointments
      • Sprays
  • Application
    • Cardiovascular Diseases
    • Central Nervous System Disorders
    • Hormonal Applications
    • Pain Management
    • Transdermal Estrogen Therapy
  • End User
    • Home Care Settings
    • Hospitals & Clinics

  • Region
    • Americas
      • Argentina
      • Brazil
      • Canada
      • Mexico
      • United States
        • California
        • Florida
        • Illinois
        • New York
        • Ohio
        • Pennsylvania
        • Texas
    • Asia-Pacific
      • Australia
      • China
      • India
      • Indonesia
      • Japan
      • Malaysia
      • Philippines
      • Singapore
      • South Korea
      • Taiwan
      • Thailand
      • Vietnam
    • Europe, Middle East & Africa
      • Denmark
      • Egypt
      • Finland
      • France
      • Germany
      • Israel
      • Italy
      • Netherlands
      • Nigeria
      • Norway
      • Poland
      • Qatar
      • Russia
      • Saudi Arabia
      • South Africa
      • Spain
      • Sweden
      • Switzerland
      • Turkey
      • United Arab Emirates
      • United Kingdom

The report offers valuable insights on the following aspects:

  1. Market Penetration: It presents comprehensive information on the market provided by key players.
  2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
  3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
  4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
  5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as:

  1. What is the market size and forecast of the Transdermal Drug Delivery System Market?
  2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Transdermal Drug Delivery System Market?
  3. What are the technology trends and regulatory frameworks in the Transdermal Drug Delivery System Market?
  4. What is the market share of the leading vendors in the Transdermal Drug Delivery System Market?
  5. Which modes and strategic moves are suitable for entering the Transdermal Drug Delivery System Market?

Table of Contents
  1. Preface
  2. Research Methodology
  3. Executive Summary
  4. Market Overview
  5. Market Insights
  6. Transdermal Drug Delivery System Market, by Type
  7. Transdermal Drug Delivery System Market, by Application
  8. Transdermal Drug Delivery System Market, by End User
  9. Americas Transdermal Drug Delivery System Market
  10. Asia-Pacific Transdermal Drug Delivery System Market
  11. Europe, Middle East & Africa Transdermal Drug Delivery System Market
  12. Competitive Landscape
  13. Competitive Portfolio
  14. List of Figures [Total: 22]
  15. List of Tables [Total: 468]
  16. List of Companies Mentioned [Total: 30]
Through thick and skin with the exceptional transdermal drug delivery system
January 29, 2024
Through thick and skin with the exceptional transdermal drug delivery system
Transdermal drug delivery system (TDDS) has sprung up as an innovative method of drug delivery with a low rejection rate, ease of administration, and great convenience. With inventions in formulations, their future is strong in the medical industry.

Transdermal drug delivery offers an engaging alternative to oral administration and injection. Over the years, TDDSs have evolved in terms of the principle of transdermal facilitation technology, and several versions of TDDSs have been derived, which have significantly enhanced transdermal efficiency and even achieved personalized controlled drug delivery.

Governments, academic institutes, and pharmaceutical companies have widely worked on bringing advancements in TDDS, and their inter-collaborations have been a cherry on top for building new TDDS histories.

In September 2023, the National Institutes for Health agency awarded Satio, Inc. a USD 3.5 million Small Business Innovation Research (SBIR) contract to develop SatioRx, a device that enables the delivery of a precise, metered dose of any liquid drug approved for transdermal delivery. With companies aiming for at-home drug and vaccine delivery, it could be a transformational potential for attaining better medical outcomes and efficiency and lowering the overall costs of healthcare.

While TDDS has made remarkable administrations in the delivery of therapeutic agents for pain management and hormonal therapy, they have found an emerging popularity in the skincare industry. Research on the mechanisms of penetration elevation, the action of chemicals within the skin, skin toxicity, and the making of novel and suitable formulations for the delivery of actives can boost the future expansion of TDDS in pharmaceutical and cosmetic arenas!

The Future of Drug Delivery System: Transdermal Skin Patches
September 26, 2023
The Future of Drug Delivery System: Transdermal Skin Patches
The demand for effective drug delivery systems has surged with the increase in the aging population and the growing prevalence of chronic diseases. Traditional methods, such as oral and injectable medication, have remained the primary approaches for drug delivery. However, these methods have several limitations, including low patient compliance, inconsistent absorption rates, and potential side effects, which have led to the development of alternative drug delivery systems, one of which is the transdermal drug delivery system. Transdermal drug delivery systems, also known as skin patches, offer a novel approach to drug delivery. These patches have been developed to administrate drugs through the skin for therapeutic purposes. They are non-invasive and convenient for patients needing long-term drug administration.

Advantages of Transdermal Drug Delivery Systems:

Transdermal drug delivery systems have numerous advantages over traditional drug delivery methods:
Transdermal patches provide a more consistent absorption rate, improving therapeutic outcomes. As patches are applied directly on the skin, the drugs bypass the liver and enter the bloodstream, avoiding first-pass metabolism, which means that patients need lower doses, leading to fewer side effects.
The patches are more convenient for patients who only need to apply them once or twice a day, increasing patient compliance and reducing the risk of missed doses.
Patches offer a non-invasive approach, eliminating the need for injections, reducing pain and discomfort, and minimizing the risk of infection.

Challenges of Transdermal Drug Delivery Systems:

Despite the advantages, transdermal drug delivery systems also face several challenges:
The skin's barrier function can make it difficult for drugs to pass through the skin, limiting the types of drugs that can be delivered via transdermal drug delivery systems.
The patches require careful attention to avoid skin irritation or allergies. The compatibility of the drug with the patch material must also be considered.
Developing and manufacturing patches can cost more than traditional drug delivery systems.

Future of Transdermal Drug Delivery Systems:

The future of transdermal drug delivery systems looks bright. Transdermal patches are becoming increasingly popular and have already been successfully used to deliver various types of drugs, such as hormones, analgesics, and anti-inflammatory drugs. With advancements in patch technology and materials, it is possible that more drugs can be delivered through the skin. Moreover, the market for transdermal patches is expected to grow, driven by the demand for easy-to-use and non-invasive drug delivery systems.
Several patches have already received FDA approval, while others are currently under development. These include patches that measure glucose levels, smart patches that detect infections, and patches that simultaneously deliver multiple drugs. These innovations indicate that the future of transdermal drug delivery systems is promising and could revolutionize the pharmaceutical industry.

Transdermal drug delivery systems offer a promising alternative to traditional drug delivery methods. They provide:

A more consistent absorption rate.
Higher patient compliance.
A non-invasive approach to drug delivery.

Although the technology is still evolving, transdermal patches will undoubtedly become an essential drug delivery system in the pharmaceutical industry. With advancements in patch technology, the potential for transdermal drug delivery systems to deliver drugs previously unattainable through traditional delivery methods is exciting. The future looks optimistic for transdermal drug delivery systems, and we can expect to see more innovations in the coming years.

Frequently Asked Questions
  1. How big is the Transdermal Drug Delivery System Market?
    Ans. The Global Transdermal Drug Delivery System Market size was estimated at USD 6.98 billion in 2023 and expected to reach USD 7.32 billion in 2024.
  2. What is the Transdermal Drug Delivery System Market growth?
    Ans. The Global Transdermal Drug Delivery System Market to grow USD 9.87 billion by 2030, at a CAGR of 5.06%
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