[190 Pages Report] The Vascular Graft Market size was estimated at USD 3.51 billion in 2023 and expected to reach USD 3.77 billion in 2024, at a CAGR 7.39% to reach USD 5.79 billion by 2030.
A vascular graft is a surgical process that redirects blood flow around a blocked or partially blocked artery in the heart by using a blood vessel taken from another part of your body, also known as a graft. Vascular grafts can be made from various materials, including synthetic polymers, such as polytetrafluoroethylene (PTFE) and polyurethane, and biological materials, such as collagen and human or animal tissue. The rise in the prevalence of vascular disorders and the rise in the geriatric population prone to cardiovascular diseases increases the adoption of vascular grafts. However, the risk of complications post-implantation of a vascular graft, such as graft infection and blood clots, may further hinder the adoption of the vascular graft. Nevertheless, the rise of biomaterial research for developing advanced, biocompatible grafts and the ongoing advancements in vascular imaging technologies such as 3D angiography offer potential for significant growth opportunities for the market.
The vascular graft market is evolving in the Americas owing to technological advancements, rising healthcare expenditure, and the prevalence of cardiovascular disorders and diabetes in the region. Strong focus on regulatory compliance and safety measures, substantial research and development projects, increasing awareness regarding vascular grafts, and growing healthcare infrastructure encourage using vascular graft procedures to improve treatment outcomes in the EMEA region. Growing prevalence of lifestyle diseases and the accelerating expansion of healthcare services, significant medical technology advancements are resulting in the development of enhanced vascular graft procedures in the APAC region. Besides, the development of bioengineered vascular grafts that mimic the natural blood vessel structure and composition is anticipated to increase the use of this medical procedure by health professionals to treat various medical conditions.
The market dynamics represent an ever-changing landscape of the Vascular Graft Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.
- Market Drivers
- Increasing prevalence of lifestyle-related disorders globally
- Growing preference for minimally invasive procedures
- Rising number of clinical trials of vascular grafts
- Market Restraints
- High treatment cost of vascular graft procedures
- Market Opportunities
- Improvements in the design and performance of vascular grafts
- Development of tissue-engineered vascular grafts
- Market Challenges
- Infections associated with vascular grafts
Raw Material: Burgeoning utilization of polytetrafluoroethylene-based vascular grafts owing to their biocompatibility and flexibility
The vascular grafts made from biological materials, including human saphenous and umbilical veins, are used widely due to their inherent compatibility and decreased chances of rejection in the human body. They display moderate compliance, excellent long-term patency, and minimal antigenicity. These materials are preferred for vascular grafts that require a smaller diameter, such as lower extremity bypass procedures or coronary artery bypass grafting. Tissue-engineered materials are engineered to mimic the natural body tissue and have the advantage of being biocompatible and biodegradable. The goal of tissue-engineered grafts is to provide a living, autologous construct that could grow with the patient, remodel, and repair itself while reducing the risk of graft failure, infection, and rejection. Polyester grafts exhibit enhanced tensile strength; they tend to be less compliant than natural blood vessels. PTFE, on the other hand, while not as durable as polyester, presents high hemocompatibility and is more commonly used due to its flexibility and superior biocompatibility. Polyurethane is a useful material due to its tunable properties, including variable hardness, flexibility, elasticity, and biostability.
Product: Proliferating usage of peripheral vascular graft for restoring blood flow in patients with blockages in the peripheral arteries
Coronary Artery Bypass Graft (CABG) is a surgically created connection between the coronary artery and aorta or larger veins that enables blood flow to bypass blockage in the heart. CABG is generally preferred when the patient has multiple artery diseases, left main coronary artery disease, or severe symptoms of coronary artery disease. An endovascular stent graft is a tube comprised of fabric supported by a metal mesh used to treat ailments such as abdominal aortic aneurysms. The patient population with a high surgical risk or refusal of open surgery prefers this. Hemodialysis access grafts are surgically implanted to provide a durable and reliable access point for hemodialysis treatments in patients with chronic kidney disease. They are preferred when patients' vessels are not suitable for creating arteriovenous (AV) fistula. Peripheral vascular grafts help restore blood flow to the parts of the body other than the brain and the heart. Used primarily in cases of peripheral artery disease, these grafts prove beneficial for patients with blockages in the peripheral arteries.
Application: Significant use of vascular grafts in treating cardiovascular diseases
Aneurysms, defined as abnormal extensions or bulges in blood vessel walls, often require intervention through vascular grafts. These grafts, utilizing synthetic materials or autogenous tissue, are used to bypass the aneurysmal site, helping to prevent rupture and subsequent serious consequences. New developments in the field have led to the creation of endovascular stent grafts for treating abdominal and thoracic aortic aneurysms, offering a less invasive alternative to traditional open surgery. Cardiovascular disease is another area where vascular grafts have a pivotal role. Coronary artery disease, peripheral artery disease, and massive myocardial infarction necessitate the use of these grafts. Surgeons utilize them for procedures such as coronary artery bypass grafting (CABG) and peripheral bypass procedures, restoring blood flow to ischemic areas, subsequently reducing cardiac morbidity and mortality. Diabetes often leads to peripheral vascular disease characterized by occlusive and stenotic lesions in the peripheral arteries. Vascular grafts, including autologous veins and synthetic materials, are used for bypassing these occluded sections, helping restore perfusion and reducing the risk of limb amputations. Renal or kidney failure, specifically end-stage renal disease (ESRD), requires life-saving hemodialysis. This process mandates reliable vascular access, achieved through the creation of arteriovenous fistulae (AVF) or grafts (AVG) for continuous dialysis access. Vascular occlusion, relating to blockage or closure of blood vessels, is a common condition necessitating the use of vascular grafts. Vascular grafts serve as conduits to restore blood flow, able to withstand the body's natural hemodynamic forces. Intraluminal stent grafts or bypass grafts, comprising biological, biocompatible, or synthetic materials, are often employed depending on the location and extent of occlusion.
End-User: Significant applications of vascular grafts in ambulatory surgical centers (ASCs)
Ambulatory Surgical Centers (ASCs) commonly perform procedures such as bypass surgery or placing stents, which often require the implantation of vascular grafts. The ASGs are witnessing a surge in vascular graft usage due to their focus on providing cost-effective, high-quality care that results in improved recovery and better patient satisfaction. Hospital-based procedures requiring vascular grafts remain high, with a constantly growing need due to complex surgeries being performed. Grafts deployed in the hospital setting often need to serve diverse surgical requirements, necessitating a broad portfolio of options. Hospitals have been traditionally more centered on complicated surgeries requiring vascular grafts. However, the rise in minimally invasive procedures and the trend towards cost-saving is shifting preferences towards ASCs.
The market disruption analysis delves into the core elements associated with market-influencing changes, including breakthrough technological advancements that introduce novel features, integration capabilities, regulatory shifts that could drive or restrain market growth, and the emergence of innovative market players challenging traditional paradigms. This analysis facilitates a competitive advantage by preparing players in the Vascular Graft Market to pre-emptively adapt to these market-influencing changes, enhances risk management by early identification of threats, informs calculated investment decisions, and drives innovation toward areas with the highest demand in the Vascular Graft Market.
The porter's five forces analysis offers a simple and powerful tool for understanding, identifying, and analyzing the position, situation, and power of the businesses in the Vascular Graft Market. This model is helpful for companies to understand the strength of their current competitive position and the position they are considering repositioning into. With a clear understanding of where power lies, businesses can take advantage of a situation of strength, improve weaknesses, and avoid taking wrong steps. The tool identifies whether new products, services, or companies have the potential to be profitable. In addition, it can be very informative when used to understand the balance of power in exceptional use cases.
The value chain of the Vascular Graft Market encompasses all intermediate value addition activities, including raw materials used, product inception, and final delivery, aiding in identifying competitive advantages and improvement areas. Critical path analysis of the <> market identifies task sequences crucial for timely project completion, aiding resource allocation and bottleneck identification. Value chain and critical path analysis methods optimize efficiency, improve quality, enhance competitiveness, and increase profitability. Value chain analysis targets production inefficiencies, and critical path analysis ensures project timeliness. These analyses facilitate businesses in making informed decisions, responding to market demands swiftly, and achieving sustainable growth by optimizing operations and maximizing resource utilization.
The pricing analysis comprehensively evaluates how a product or service is priced within the Vascular Graft Market. This evaluation encompasses various factors that impact the price of a product, including production costs, competition, demand, customer value perception, and changing margins. An essential aspect of this analysis is understanding price elasticity, which measures how sensitive the market for a product is to its price change. It provides insight into competitive pricing strategies, enabling businesses to position their products advantageously in the Vascular Graft Market.
The technology analysis involves evaluating the current and emerging technologies relevant to a specific industry or market. This analysis includes breakthrough trends across the value chain that directly define the future course of long-term profitability and overall advancement in the Vascular Graft Market.
The patent analysis involves evaluating patent filing trends, assessing patent ownership, analyzing the legal status and compliance, and collecting competitive intelligence from patents within the Vascular Graft Market and its parent industry. Analyzing the ownership of patents, assessing their legal status, and interpreting the patents to gather insights into competitors' technology strategies assist businesses in strategizing and optimizing product positioning and investment decisions.
The trade analysis of the Vascular Graft Market explores the complex interplay of import and export activities, emphasizing the critical role played by key trading nations. This analysis identifies geographical discrepancies in trade flows, offering a deep insight into regional disparities to identify geographic areas suitable for market expansion. A detailed analysis of the regulatory landscape focuses on tariffs, taxes, and customs procedures that significantly determine international trade flows. This analysis is crucial for understanding the overarching legal framework that businesses must navigate.
The regulatory framework analysis for the Vascular Graft Market is essential for ensuring legal compliance, managing risks, shaping business strategies, fostering innovation, protecting consumers, accessing markets, maintaining reputation, and managing stakeholder relations. Regulatory frameworks shape business strategies and expansion initiatives, guiding informed decision-making processes. Furthermore, this analysis uncovers avenues for innovation within existing regulations or by advocating for regulatory changes to foster innovation.
The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Vascular Graft Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Vascular Graft Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Aquedeon Medical, Inc. Receives FDA IDE Approval for the Duett Vascular Graft System
Aquedeon Medical, Inc. has received FDA Investigational Device Exemption (IDE) approval to conduct a staged pivotal clinical trial for its Duett Vascular Graft System in the United States. The Duett Vascular Graft System is designed with the aim of standardizing and simplifying open surgical thoracic aortic procedures. It achieves this by connecting native aortic arch branch vessels to the surgical graft without the need for suturing each anastomosis. This innovative approach has the potential to decrease deep hypothermic circulatory arrest (DHCA) and overall procedure time, thus reducing the risk of severe complications. [Published On: 2023-08-23]
Xeltis’ aXess Vascular Graft Development Receives Funding From European Innovation Council
Vascular Graft Xeltis, a Netherlands-based developer of cardiovascular living implants, received Euro 12.5 million in funding from the European Innovation Council (EIC) Fund to support vital clinical trials of its vascular graft product, aXess. These trials include a first-in-human (FIH) trial for patients with Chronic Kidney Disease requiring hemodialysis, as well as a pivotal trial enrolling patients across Europe. [Published On: 2023-08-14]
Vygon Partners with Carmat to Develop a Vascular Graft for an Artificial Heart
Vygon has partnered with Carmat to develop two prosthetic outflow tracts for their Aeson artificial heart device. By the fourth quarter of 2024, Vygon plans to utilize its existing vascular graft and create a second bespoke device. The Aeson device is currently available in the European Union and is undergoing evaluation in the United States through an early feasibility study. [Published On: 2023-06-22]
The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Vascular Graft Market. This critical assessment involves a thorough analysis of the organization’s resources, capabilities, and overall performance to identify its core strengths and areas for improvement.
The report delves into recent significant developments in the Vascular Graft Market, highlighting leading vendors and their innovative profiles. These include Vascular Graft Solutions Ltd., Medtronic PLC, Boston Scientific Corporation, W. L. Gore & Associates, Inc., Corcym S.r.l., Cardinal Health Inc., Xeltis B.V., Endologix Inc., B. Braun Melsungen AG, Rua Life Sciences PLC, Terumo Corporation, Cook Medical, Inc., Affluent Medical, Abbott Laboratories, Getinge AB, Lemaitre Vascular, Inc., Becton, Dickinson and Company, Merit Medical Systems, Inc., Shanghai Suokang Medical Implants Co. Ltd., Perouse Medical SAS by Vygon SAS, VUP Medical, Heart Medical Europe B.V., Japan Lifeline Co., Ltd., CryoLife, Inc., and BIOVIC Sdn. Bhd..
This research report categorizes the Vascular Graft Market to forecast the revenues and analyze trends in each of the following sub-markets:
- Raw Material
- Biological Materials
- Human Saphenous & Umbilical Veins
- Tissue Engineered Materials
- Polyester
- Polytetrafluoroethylene
- Polyurethane
- Biological Materials
- Product
- Coronary Artery By-Pass Graft
- Endovascular Stent Graft
- Hemodialysis Access Graft
- Peripheral Vascular Graft
- Application
- Aneurysm
- Cardiovascular
- Diabetes
- Kidney Failure
- Vascular Occlusion
- End-User
- Ambulatory Surgical Center
- Hospital
- Region
- Americas
- Argentina
- Brazil
- Canada
- Mexico
- United States
- California
- Florida
- Illinois
- New York
- Ohio
- Pennsylvania
- Texas
- Asia-Pacific
- Australia
- China
- India
- Indonesia
- Japan
- Malaysia
- Philippines
- Singapore
- South Korea
- Taiwan
- Thailand
- Vietnam
- Europe, Middle East & Africa
- Denmark
- Egypt
- Finland
- France
- Germany
- Israel
- Italy
- Netherlands
- Nigeria
- Norway
- Poland
- Qatar
- Russia
- Saudi Arabia
- South Africa
- Spain
- Sweden
- Switzerland
- Turkey
- United Arab Emirates
- United Kingdom
- Americas
- Market Penetration: This section thoroughly overviews the current market landscape, incorporating detailed data from key industry players.
- Market Development: The report examines potential growth prospects in emerging markets and assesses expansion opportunities in mature segments.
- Market Diversification: This includes detailed information on recent product launches, untapped geographic regions, recent industry developments, and strategic investments.
- Competitive Assessment & Intelligence: An in-depth analysis of the competitive landscape is conducted, covering market share, strategic approaches, product range, certifications, regulatory approvals, patent analysis, technology developments, and advancements in the manufacturing capabilities of leading market players.
- Product Development & Innovation: This section offers insights into upcoming technologies, research and development efforts, and notable advancements in product innovation.
- What is the current market size and projected growth?
- Which products, segments, applications, and regions offer promising investment opportunities?
- What are the prevailing technology trends and regulatory frameworks?
- What is the market share and positioning of the leading vendors?
- What revenue sources and strategic opportunities do vendors in the market consider when deciding to enter or exit?
- Preface
- Research Methodology
- Executive Summary
- Market Overview
- Market Insights
- Vascular Graft Market, by Raw Material
- Vascular Graft Market, by Product
- Vascular Graft Market, by Application
- Vascular Graft Market, by End-User
- Americas Vascular Graft Market
- Asia-Pacific Vascular Graft Market
- Europe, Middle East & Africa Vascular Graft Market
- Competitive Landscape
- Competitive Portfolio
- List of Figures [Total: 24]
- List of Tables [Total: 470]
- List of Companies Mentioned [Total: 25]
Among the greatest challenges faced by vascular graft surgery is to provide solutions for long-term implantation without requiring excessive medical procedures. Historically, synthetic materials, such as expanded polytetrafluoroethylene (ePTFE) and polyethylene terephthalate (PET), were commonly used in the production of vascular grafts. Although these materials remained suitable for a range of surgical applications, they failed to provide optimal usage since, at times, they didn't always integrate into a single system and were not durable, resulting in repeat surgeries. Vascular graft surgery has grown significantly with the development of various bio-absorbable and natural bio-materials. With the incorporation of materials such as silk fibroin and collagen, as well as plant materials such as cellulose, greater success has been observed in both short and long-term implantation.
A recent revelation in vascular graft materials is the incorporation of smart polymers that allow a profound shift in the physical properties of the graft in response to various changes in the extracellular environment. These allow the grafts to mimic or replace the particular features of natural tissue. Smart polymers are designed to diminish catastrophic anastomotic failures by adjusting their modulus (the degree of stiffness and strength) and porosity. Various molecules, such as glucose or temperature agent components, can trigger the release of drugs to limit post-operation inflammatory responses. Such responsive polymer systems can improve the chances of long-term success in vascular graft operations and help the graft to integrate into the entire cardiovascular system.
One of the primary issues with synthetic vascular grafts is that thrombosis and intimal hyperplasia can develop. Advancements in the design of vascular grafts include the ability to regulate the mechanical forces that occur in the cardiovascular system, improving biocompatibility and thus reducing thrombosis and intimal hyperplasia. For instance, the sutureless vascular grafts technique employs interlocking valve-shaped structures in place of sutures to prevent clotting and attachment whilst increasing smooth muscle cell proliferation.
Vascular grafts produced using 3D printing technology have been an emerging area of study and application. Layer-by-layer, 3D printing provides for potential customization of graft size and structure according to targeting the particular vascular site and patient. The ability to manufacture small-diameter grafts and multiple bifurcations within a single graft is another advantage of this technology.
The future of vascular grafts is inextricably linked to advancements in scaffold material and design. The materials listed, such as natural bio-materials, smart polymers, and 3D printing, amongst others, offer to improve biocompatibility, tailor-made to the patient's needs, and achieve unparalleled long-term success for vascular graft operations. As these tools evolve, the possibilities for further progress are limitless and could soon become the hottest alternatives in the medical surgery world.
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